Category
[+]
1.1. Cell envelope and cell division
[+]
[+]
1.1.1.1. Biosynthesis of peptidoglycan
[+]
1.1.1.2. Autolytic activity required for peptidoglycan synthesis (cell elongation)
[+]
1.1.1.3. Biosynthesis of lipoteichoic acid
[+]
1.1.1.4. Biosynthesis of teichoic acid
[+]
1.1.1.5. Biosynthesis of teichuronic acid
[+]
1.1.1.6. Export of anionic polymers and attachment to peptidoglycan
[+]
1.1.1.7. Penicillin-binding proteins
[+]
1.1.1.8. Biosynthesis of the carrier lipid undecaprenylphosphate
[+]
[+]
1.1.3. Cell wall degradation/ turnover
[+]
[+]
1.1.3.2. Autolysis/ based on similarity
[+]
1.1.3.3. Utilization of cell wall components
[+]
[+]
1.1.3.5. N-acetyl-??-D-glucosaminidases
[+]
1.1.3.6. Cell wall degradation/ turnover/ Additional genes
[+]
1.1.4. Capsule biosynthesis and degradation
[+]
[+]
1.1.6. Cell wall/ other/ based on similarity
[+]
[+]
[+]
1.1.9. Cell division/ based on similarity
[+]
[+]
[+]
[+]
1.2.1.1.1. Uptake of carbon sources
1.2.1.1.2. Uptake of amino acids
1.2.1.1.4. Uptake of compatible solutes for osmoprotection
[+]
1.2.1.2.1. Efflux of antibiotics
1.2.1.2.2. Export of antibiotic substances
1.2.1.3. Regulatory ABC transporters
[+]
1.2.2. Phosphotransferase system
[+]
[+]
1.2.3.1. The general components of the ECF transporters
[+]
1.2.3.2. The substrate-specific S components of the ECF transporters
[+]
1.2.3.3. Class I ECF transporter
[+]
[+]
1.2.4.1. Amino acid transporters
[+]
[+]
1.2.4.3. Carbohydrate transporter
[+]
1.2.4.4. Transporter for organic acids
[+]
1.2.4.5. Metal ion transporter
[+]
1.2.4.6. Nucleotide/ nucleoside transporter
[+]
1.2.4.7. Transporter for cofactors
[+]
1.2.4.8. Uptake of other small ions
[+]
1.2.4.9. Uptake of compatible solutes
[+]
1.2.4.10. Siderophore exporters
[+]
[+]
[+]
[+]
[+]
1.2.4.15. Multidrug exporters/ based on homology
[+]
[+]
1.3.1. Metal ion homeostasis (K
[+]
1.3.1.1. Magnesium uptake/ efflux
[+]
1.3.1.2. Sodium uptake/ export
[+]
1.3.1.3. Potassium uptake/ export
[+]
1.3.1.4. Metal ion homeostasis/ Other
[+]
1.3.2. Trace metal homeostasis (Cu
[+]
[+]
1.3.3.1. ABC transporters for the uptake of iron/ siderophores
[+]
1.3.3.2. Elemental iron transport system
[+]
1.3.3.3. Acquisition of iron / Other
[+]
1.3.4. Acquisition of iron/ based on similarity
[+]
[+]
[+]
2.1. Electron transport and ATP synthesis
[+]
2.1.1. Regulators of electron transport
[+]
[+]
2.1.3. Electron transport/ other
[+]
2.1.4. Electron transport/ other/ based on similarity
[+]
[+]
[+]
[+]
2.2.2. Utilization of specific carbon sources
[+]
2.2.2.1. Utilization of organic acids
[+]
2.2.2.2. Utilization of acetoin
[+]
2.2.2.3. Utilization of glycerol/ glycerol-3-phosphate
[+]
2.2.2.4. Utilization of ribose
[+]
2.2.2.5. Utilization of xylan/ xylose
[+]
2.2.2.6. Utilization of arabinan/ arabinose/ arabitol
[+]
2.2.2.7. Utilization of fructose
[+]
2.2.2.8. Utilization of galactose
[+]
2.2.2.9. Utilization of mannose
[+]
2.2.2.10. Utilization of mannitol
[+]
2.2.2.11. Utilization of glucitol
[+]
2.2.2.12. Utilization of rhamnose
[+]
2.2.2.13. Utilization of gluconate
[+]
2.2.2.14. Utilization of glucarate/galactarate
[+]
2.2.2.15. Utilization of hexuronate
[+]
2.2.2.16. Utilization of inositol
[+]
2.2.2.17. Utilization of amino sugars
[+]
2.2.2.18. Utilization of beta-glucosides
[+]
2.2.2.19. Utilization of sucrose
[+]
2.2.2.20. Utilization of trehalose
[+]
2.2.2.21. Utilization of melibiose
[+]
2.2.2.22. Utilization of maltose
[+]
2.2.2.23. Utilization of starch/ maltodextrin
[+]
2.2.2.24. Utilization of galactan
[+]
2.2.2.25. Utilization of glucomannan
[+]
2.2.2.26. Utilization of pectin
[+]
2.2.2.27. Utilization of other polymeric carbohydrates
[+]
2.2.2.28. Utilization of other pentoses and hexoses
[+]
2.3. Amino acid/ nitrogen metabolism
[+]
2.3.1. Biosynthesis/ acquisition of amino acids
[+]
2.3.1.1. Biosynthesis/ acquisition of glutamate/ glutamine/ ammonium assimilation
[+]
2.3.1.2. Biosynthesis/ acquisition of proline
[+]
2.3.1.3. Biosynthesis/ acquisition of proline/ based on similarity
[+]
2.3.1.4. Biosynthesis/ acquisition of arginine
[+]
2.3.1.5. Biosynthesis/ acquisition of aspartate/ asparagine
[+]
2.3.1.6. Biosynthesis/ acquisition of lysine/ threonine
[+]
2.3.1.7. Biosynthesis/ acquisition of lysine/ threonine/ based on similarity
[+]
2.3.1.8. Biosynthesis/ acquisition of serine/ glycine/ alanine
[+]
2.3.1.9. Biosynthesis/ acquisition of cysteine
[+]
2.3.1.10. Biosynthesis/ acquisition of methionine/ S-adenosylmethionine
[+]
2.3.1.11. Biosynthesis/ acquisition of methionine/ S-adenosylmethionine/ based on similarity
[+]
2.3.1.12. Biosynthesis/ acquisition of branched-chain amino acids
[+]
2.3.1.13. Biosynthesis/ acquisition of aromatic amino acids
[+]
2.3.1.14. Biosynthesis/ acquisition of histidine
[+]
2.3.2. Utilization of amino acids
[+]
2.3.2.1. Utilization of glutamine/ glutamate
[+]
2.3.2.2. Utilization of proline
[+]
2.3.2.3. Utilization of proline/ based on similarity
[+]
2.3.2.4. Utilization of arginine/ ornithine
[+]
2.3.2.5. Utilization of histidine
[+]
2.3.2.6. Utilization of asparagine/ aspartate
[+]
2.3.2.7. Utilization of alanine/ serine
[+]
2.3.2.8. Utilization of threonine/ glycine
[+]
2.3.2.9. Utilization of branched-chain amino acids
[+]
2.3.2.10. Utilization of gamma-amino butyric acid
[+]
2.3.3. Utilization of nitrogen sources other than amino acids
[+]
2.3.3.1. Utilization of nitrate/ nitrite
[+]
[+]
2.3.3.3. Utilization of amino sugars
[+]
2.3.3.4. Utilization of peptides
[+]
2.3.3.5. Utilization of proteins
[+]
2.3.4. Putative amino acid transporter
[+]
[+]
[+]
2.4.1.1. Utilization of phospholipids
[+]
2.4.1.2. Utilization of phospholipids/ based on similarity
[+]
2.4.1.3. Utilization of fatty acids
[+]
2.4.1.4. Utilization of lipids/ other
[+]
[+]
2.4.2.1. Biosynthesis of fatty acids
[+]
2.4.2.2. Biosynthesis of phospholipids
[+]
2.4.2.3. Biosynthesis of isoprenoids
[+]
2.4.3. Lipid metabolism/ other
[+]
[+]
2.5.1. Utilization of nucleotides
[+]
2.5.2. Biosynthesis/ acquisition of nucleotides
[+]
2.5.2.1. Biosynthesis/ acquisition of purine nucleotides
[+]
2.5.2.2. Biosynthesis/ acquisition of purine nucleotides/ based on similarity
[+]
2.5.2.3. Purine salvage and interconversion
[+]
2.5.2.4. Biosynthesis/ acquisition of pyrimidine nucleotides
[+]
2.5.2.5. Biosynthesis/ acquisition of nucleotides/ other
[+]
2.5.2.6. Biosynthesis/ acquisition of nucleotides/ other/ based on similarity
[+]
2.5.3. Metabolism of signalling nucleotides
[+]
2.5.4. Nucleotide metabolism/ other
[+]
2.6. Additional metabolic pathways
[+]
2.6.1. Biosynthesis of cell wall components
[+]
2.6.1.1. Biosynthesis of peptidoglycan
[+]
2.6.1.2. Biosynthesis of lipoteichoic acid
[+]
2.6.1.3. Biosynthesis of teichoic acid
[+]
2.6.1.4. Biosynthesis of teichuronic acid
[+]
2.6.1.5. Biosynthesis of the carrier lipid undecaprenylphosphate
[+]
2.6.2. Biosynthesis of cofactors
[+]
2.6.2.1. Biosynthesis/ acquisition of biotin
[+]
2.6.2.2. Biosynthesis/ acquisition of riboflavin/ FAD
[+]
2.6.2.3. Biosynthesis/ acquisition of thiamine
[+]
2.6.2.4. Biosynthesis of coenzyme A
[+]
2.6.2.5. Biosynthesis of folate
[+]
2.6.2.6. Biosynthesis of heme/ siroheme
[+]
2.6.2.7. Biosynthesis of lipoic acid
[+]
2.6.2.8. Biosynthesis of menaquinone
[+]
2.6.2.9. Biosynthesis of menaquinone/ based on similarity
[+]
2.6.2.10. Biosynthesis of molybdopterin
[+]
2.6.2.11. Biosynthesis of NAD(P)
[+]
2.6.2.12. Biosynthesis of pyridoxal phosphate
[+]
[+]
[+]
2.6.4.1. Conversion of S-methyl cysteine to cysteine
[+]
2.6.4.2. sulfur metabolism/ general
[+]
2.6.4.3. Conversion of S-(2-succino)cysteine to cysteine
[+]
[+]
2.6.5.1. Acquisition of iron / Other
[+]
2.6.5.2. Acquisition of iron/ based on similarity
[+]
2.6.5.3. Biosynthesis of iron-sulfur clusters
[+]
2.6.5.4. ABC transporters for the uptake of iron/ siderophores
[+]
2.6.5.5. Elemental iron transport system
[+]
[+]
2.6.6. Miscellaneous metabolic pathways
[+]
2.6.6.1. Biosynthesis of antibacterial compounds
[+]
2.6.6.2. Biosynthesis of bacillithiol
[+]
2.6.6.3. Biosynthesis of dipicolinate
[+]
2.6.6.4. Biosynthesis of glycine betaine
[+]
2.6.6.5. Biosynthesis of glycogen
[+]
2.6.6.6. Metabolism of polyamines
[+]
2.6.6.7. Biosynthesis of rhamnose (for the exosporium)
[+]
[+]
[+]
[+]
[+]
3.1.2. DNA replication/ based on similarity
[+]
3.1.3. DNA condensation/ segregation
[+]
3.1.4. DNA restriction/ modification
[+]
3.1.5. DNA repair/ recombination
[+]
3.1.5.1. Excision of prophages
[+]
[+]
3.1.5.3. Spore-encoded non-homologous end joining system
[+]
3.1.5.4. Double strand breaks repair
[+]
3.1.5.5. Oxidized guanine (GO) DNA repair system
[+]
[+]
3.1.5.7. Mismatch repair (MMR)
[+]
3.1.6. DNA repair/ recombination/ based on similarity
[+]
[+]
3.1.8. Genetics/ other/ based on similarity
[+]
3.1.9. Newly identified competence genes
[+]
3.2. RNA synthesis and degradation
[+]
[+]
[+]
[+]
[+]
3.2.5. RNase/ based on similarity
[+]
[+]
[+]
[+]
3.3.1.2. rRNA modification and maturation
[+]
3.3.1.3. rRNA modification and maturation/ based on similarity
[+]
[+]
3.3.1.5. Ribosomal protein/ based on similarity
[+]
[+]
[+]
3.3.1.8. tRNA modification and maturation
[+]
3.3.1.9. tRNA modification and maturation/ based on similarity
[+]
3.3.1.10. Aminoacyl-tRNA synthetases
[+]
[+]
[+]
3.3.1.13. Translation/ other/ based on similarity
[+]
3.3.1.14. Translation factor modification and maturation
[+]
3.3.2. Chaperones/ protein folding
[+]
3.3.3. Chaperone/ protein folding/ based on similarity
[+]
[+]
[+]
[+]
3.3.4.3. Protein kinase/ based on similarity
[+]
[+]
3.3.4.5. Protein acetylases/ deacetylases
[+]
3.3.4.6. Protein acetylase/ deacetylase/ based on similarity
[+]
[+]
3.3.4.8. Protein modification/ other
[+]
[+]
3.3.6. Protein secretion/ based on similarity
[+]
[+]
3.4. Regulation of gene expression
[+]
3.4.1. Sigma factors and their control
[+]
3.4.2. Transcription factors and their control
[+]
3.4.2.1. Two-component system response regulators
[+]
3.4.2.2. Control of two-component response regulators
[+]
[+]
3.4.2.4. Control of PRD-type regulators
[+]
3.4.2.5. Transcription factors/ other
[+]
3.4.2.6. Transcription factor/ other/ based on similarity
[+]
3.4.2.7. Control of transcription factor (other than two-component system)
[+]
[+]
[+]
[+]
3.4.3.3. Trigger enzymes that act directly as transcription factors by binding DNA
[+]
3.4.3.4. Trigger enzyme that acts by binding of a specific RNA element
[+]
3.4.3.5. Trigger enzymes that control transcription in a yet unknown way
[+]
[+]
3.4.5. Regulators of core metabolism
[+]
3.4.6. Transition state regulators
[+]
[+]
[+]
3.4.7.2. Proteins controlling the activity of the kinases
[+]
3.4.7.3. The phosphotransferases
[+]
[+]
3.4.7.5. Phosphatases controlling the phosphorelay
[+]
3.4.7.6. Other protein controlling the activity of the phosphorelay
[+]
[+]
[+]
[+]
4.1. Exponential and early post-exponential lifestyles
[+]
4.1.1. Motility and chemotaxis
[+]
4.1.1.1. Signal transduction in motility and chemotaxis
[+]
4.1.1.1.1. Soluble signalling proteins
4.1.1.1.3. Soluble chemoreceptors
4.1.1.1.4. Membrane-bound chemoreceptors
4.1.1.1.5. Additional chemotaxis signal transduction and regulatory proteins
[+]
4.1.1.3. Flagellar proteins/ based on similarity
[+]
4.1.1.4. Motility and chemotaxis/ other
[+]
[+]
4.1.2.1. Matrix polysaccharide synthesis
[+]
4.1.2.2. Amyloid protein synthesis
[+]
4.1.2.3. Repellent surface layer
[+]
[+]
4.1.2.5. Other proteins required for biofilm formation
[+]
4.1.2.6. Other proteins required for efficient pellicle biofilm formation
[+]
[+]
[+]
[+]
[+]
[+]
[+]
4.2.1.2. Spore coat protein/ based on similarity
[+]
4.2.1.3. Small acid-soluble spore proteins
[+]
4.2.1.4. Sporulation proteins/ other
[+]
4.2.1.5. Newly identified sporulation proteins (based on transcription profiling)
[+]
[+]
[+]
4.2.2.2. Proteins controlling the activity of the kinases
[+]
4.2.2.3. The phosphotransferases
[+]
[+]
4.2.2.5. Phosphatases controlling the phosphorelay
[+]
4.2.2.6. Other protein controlling the activity of the phosphorelay
[+]
[+]
[+]
4.2.5. Germination/ based on similarity
[+]
[+]
4.3.1. General stress proteins (controlled by SigB)
[+]
4.3.2. Cell envelope stress proteins (controlled by SigM
[+]
4.3.3. Acid stress proteins (controlled by YvrI-YvrHa)
[+]
[+]
[+]
4.3.6. Coping with hyper-osmotic stress
[+]
4.3.7. Coping with hypo-osmotic stress
[+]
4.3.8. Resistance against oxidative and electrophile stress
[+]
4.3.9. Resistance against oxidative and electrophile stress/ based on similarity
[+]
4.3.10. Resistance against other toxic compounds (nitric oxide
[+]
4.3.11. Resistance against toxic metals
[+]
4.3.12. Resistance against toxic metals/ based on similarity
[+]
4.3.13. Resistance against toxins/ antibiotics
[+]
4.3.14. Resistance against toxins/ antibiotics/ based on similarity
[+]
4.3.15. Biosynthesis of antibacterial compounds
[+]
4.3.16. Biosynthesis of antibacterial compounds/ based on similarity
[+]
[+]
[+]
4.4. Lifestyles/ miscellaneous
[+]
[+]
[+]
[+]
[+]
[+]
[+]
6.4.1. Phosphorylation on an Arg residue
[+]
6.4.2. Phosphorylation on an Asp residue
[+]
6.4.3. Phosphorylation on a Cys residue
[+]
6.4.4. Phosphorylation on a His residue
[+]
6.4.5. Phosphorylation on a Ser residue
[+]
6.4.6. Phosphorylation on a Thr residue
[+]
6.4.7. Phosphorylation on a Tyr residue
[+]
6.4.8. Phosphorylation on either a Ser
[+]
6.4.9. Phosphoproteins / Other
[+]
6.5. Universally conserved proteins
[+]
6.6. Poorly characterized/ putative enzymes
[+]
6.7. Proteins of unknown function
[+]
[+]
[+]
[+]
[+]
6.9.3. Small cytoplasmatic RNA
[+]
6.9.4. RNA component of RNase P
[+]
[+]
6.9.6. Antisense RNAs of toxin/antitoxin systems
[+]
6.9.7. Small RNAs with unknown functions
[+]
[+]
[+]
[+]