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bacA

bacilysin biosynthesis protein BacA
genebacA
locusRBAM_034930
feature typeCDS
productABS75822.2 bacilysin biosynthesis protein BacA
synonyms
homologBSU37740
start3599166
stop3599780
direction-
length624
essential
protein detected in LBnot detected
Genomic Context

Functional category containing this gene/protein

CategoryMetabolism
Subcategory1additional metabolic pathways
Subcategory2miscellaneous metabolic pathways
Subcategory3biosynthesis of antibacterial compounds

Phenotypes of a mutant

plant-bacteria interaction

biocontrol action: antibacterial bacilysin acts against several plant pathogens and cyanobacterial bloom in freshwater

Expression and Regulation

Operons
bacA-bacB-bacC-bacD-bacE-bacF
Transcripts
Primary TSS3599803
Secondary TSS
Internal TSS
Antisense TSS

Sigma factors

SigA

Protein regulator

AbrB repression CodY repression ScoC repression

Additional regulation

RNA regulation_mode

This gene is a member of the following regulons

SigA Regulon
The protein


Catalyzed reaction/ biological activity
E.C. number
Protein family
Domains
Effectors of protein activity
Refer to BSU37740
Structure
Refer to BSU37740
Malonylation
Acetylation
Localization

Biological materials


Mutant
LacZ fusion
GFP fusion
FLAG-tag construct
Antibody
Additional information
no ortholog in B. subtilis 168

References


Wu L, Wu H, Chen L, Yu X, Borriss R, Gao X.

Difficidin and bacilysin from Bacillus amyloliquefaciens FZB42 have antibacterial activity against Xanthomonas oryzae rice pathogens.

Sci Rep. 2015 Aug 13;5:12975. doi: 10.1038/srep12975;PMID:26268540

Scholz R, Molohon KJ, Nachtigall J, Vater J, Mark

"Plantazolicin, a novel microcin B17/streptolysin S-like natural product from Bacillus amyloliquefaciens FZB42."

J Bacteriol. 2011 Jan;193(1):215-24. doi: 10.1128/JB.00784-10. Epub 2010 Oct 22;PMID:20971906

Chen XH, Scholz R, Borriss M, Junge H, M?gel G, K

Difficidin and bacilysin produced by plant-associated Bacillus amyloliquefaciens are efficient in controlling fire blight disease.

J Biotechnol. 2009 Mar 10;140(1-2):38-44. doi: 10.1016/j.jbiotec.2008.10.015. Epub 2008 Nov 18;PMID:19061923

Chen XH, Koumoutsi A, Scholz R, Borriss R.

More than anticipated - production of antibiotics and other secondary metabolites by Bacillus amyloliquefaciens FZB42.

J Mol Microbiol Biotechnol. 2009;16(1-2):14-24. doi: 10.1159/000142891. Epub 2008 Oct 29.;PMID:18957859