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baeJ

NRPS/PKS hybrid protein involved in bacillaene synthesis
genebaeJ
locusRBAM_016980
feature typeCDS
productABS74061.1 non-ribosomal peptide synthetase
synonyms
homolog
start1708763
stop1723711
direction+
length14949
essential
protein detected in LBnot detected
Genomic Context

Functional category containing this gene/protein

Category
Subcategory1
Subcategory2
Subcategory3

Phenotypes of a mutant

plant-bacteria interaction

biocontrol of plant pathogens

Expression and Regulation

Operons
pksC-pksD-pksE-acpK-pksF-pksG-
Transcripts
Primary TSS
Secondary TSS
Internal TSS1717258
Antisense TSS1712294

Sigma factors

Protein regulator

Additional regulation

RNA regulation_mode

This gene is a member of the following regulons

The protein


Catalyzed reaction/ biological activity
E.C. number
Protein family
Domains
Effectors of protein activity
Structure
Malonylation
"K548,1299,3894,4335"
Acetylation
"K19,74,555,642,978,1128,1511,1514,1664,2040,2207,
Localization

Biological materials


Mutant
LacZ fusion
GFP fusion
FLAG-tag construct
Antibody
Additional information

References


Fan B, Li Y, Li L, P X,Bu C,Wu X, Borriss R.

Malonylome analysis of rhizobacterium Bacillus amyloliquefaciens FZB42 reveals involvement of lysine malonylation in polyketide synthesis and plant-bacteria interactions

J Proteomics. 2017 Feb 10;154:1-12. doi: 10.1016/j.jprot.2016.11.022;PMID:27939684

Liu L, Wang G, Song L, Lv B, Liang W

Acetylome analysis reveals the involvement of lysine acetylation in biosynthesis of antibiotics in Bacillus amyloliquefaciens.

Sci Rep. 2016 Jan 29;6:20108. doi: 10.1038/srep20108;PMID:26822828

Wu L, Wu H, Chen L, Yu X, Borriss R, Gao X.

Difficidin and bacilysin from Bacillus amyloliquefaciens FZB42 have antibacterial activity against Xanthomonas oryzae rice pathogens.

Sci Rep. 2015 Aug 13;5:12975. doi: 10.1038/srep12975;PMID:26268540

Schneider K, Chen XH, Vater J, Franke P, Nicholso

Macrolactin is the polyketide biosynthesis product of the pks2 cluster of Bacillus amyloliquefaciens FZB42.

J Nat Prod. 2007 Sep;70(9):1417-23. Epub 2007 Sep 11.;PMID:17827323

Butcher RA, Schroeder FC, Fischbach MA, Straight

"The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis."

Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1506-9. Epub 2007 Jan 18.;PMID:17234808