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baeM

polyketide synthase of type I involved in bacillaene synthesis
genebaeM
locus (old tag)RBAM_RS08495 (RBAM_017000)
feature typeCDS_with protein
productWP_012117597.1; KR domain-containing protein
synonyms
homolog
start1737151
stop1747686
direction+
length10536
essentialno
protein detection in LByes
Genomic Context

Functional category containing this gene/protein

Category2. Metabolism
Subcategory12.6. Additional metabolic pathways
Subcategory22.6.6. Miscellaneous metabolic pathways
Subcategory32.6.6.1. Nonribosomal synthesis of antibacterial p

Phenotypes of a mutant

plant-bacteria interaction

biocontrol of plant pathogens

Expression and Regulation

Operons
pksC-pksD-pksE-acpK-pksF-pksG-
Transcripts
Primary TSS
Secondary TSS
Internal TSS
Antisense TSS

Sigma factors

Protein regulator

Additional regulation

RNA regulation_mode

This gene is a member of the following regulons

The protein


Catalyzed reaction/ biological activity
E.C. number
Protein family
Domains
Effectors of protein activity
Structure
Modification
K358,434,442,1330,1605,2136,2249,2261,2901,2924,3
Acetylation
K425,757,761,1605,2602
Localization

Biological materials


Mutant
LacZ fusion
GFP fusion
FLAG-tag construct
Antibody
Additional information

References


Fan B, Li Y, Li L, P X,Bu C,Wu X, Borriss R.

Malonylome analysis of rhizobacterium Bacillus amyloliquefaciens FZB42 reveals involvement of lysine malonylation in polyketide synthesis and plant-bacteria interactions

J Proteomics. 2017 Feb 10;154:1-12. doi: 10.1016/j.jprot.2016.11.022;PMID:27939684

Liu L, Wang G, Song L, Lv B, Liang W

Acetylome analysis reveals the involvement of lysine acetylation in biosynthesis of antibiotics in Bacillus amyloliquefaciens.

Sci Rep. 2016 Jan 29;6:20108. doi: 10.1038/srep20108;PMID:26822828

Wu L, Wu H, Chen L, Yu X, Borriss R, Gao X.

Difficidin and bacilysin from Bacillus amyloliquefaciens FZB42 have antibacterial activity against Xanthomonas oryzae rice pathogens.

Sci Rep. 2015 Aug 13;5:12975. doi: 10.1038/srep12975;PMID:26268540

Butcher RA, Schroeder FC, Fischbach MA, Straight

"The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis."

Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1506-9. Epub 2007 Jan 18.;PMID:17234808