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dfnD

modular polyketide synthase of type I involved in difficidin synthesis DfnD
genedfnD
locusRBAM_022030
feature typeCDS
productABS74564.1 SDR family NAD(P)-dependent oxidoreductase
synonyms
homolog
start2327951
stop2340541
direction-
length12591
essential
protein detected in LByes
Genomic Context

Functional category containing this gene/protein

Category
Subcategory1
Subcategory2
Subcategory3

Phenotypes of a mutant

plant-bacteria interaction

control of plant pathogens

Expression and Regulation

Operons
Transcripts
Primary TSS
Secondary TSS
Internal TSS
Antisense TSS2335459

Sigma factors

Protein regulator

Additional regulation

RNA regulation_mode

This gene is a member of the following regulons

The protein


Catalyzed reaction/ biological activity
E.C. number
Protein family
Domains
Effectors of protein activity
Structure
Malonylation
"K2,85,256,336,495,992,1847,1993,2076"
Acetylation
Localization

Biological materials


Mutant
LacZ fusion
GFP fusion
FLAG-tag construct
Antibody
Additional information

References


Fan B, Li Y, Li L, P X,Bu C,Wu X, Borriss R.

Malonylome analysis of rhizobacterium Bacillus amyloliquefaciens FZB42 reveals involvement of lysine malonylation in polyketide synthesis and plant-bacteria interactions

J Proteomics. 2017 Feb 10;154:1-12. doi: 10.1016/j.jprot.2016.11.022;PMID:27939684

Wu L, Wu H, Chen L, Yu X, Borriss R, Gao X.

Difficidin and bacilysin from Bacillus amyloliquefaciens FZB42 have antibacterial activity against Xanthomonas oryzae rice pathogens.

Sci Rep. 2015 Aug 13;5:12975. doi: 10.1038/srep12975;PMID:26268540

Schneider K, Chen XH, Vater J, Franke P, Nicholso

Macrolactin is the polyketide biosynthesis product of the pks2 cluster of Bacillus amyloliquefaciens FZB42.

J Nat Prod. 2007 Sep;70(9):1417-23. Epub 2007 Sep 11.;PMID:17827323