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mlnB

polyketide synthase of type I involved in macrolactin synthesis
genemlnB
locusRBAM_014340
feature typeCDS
productABS73797.1 SDR family NAD(P)-dependent oxidoreductase
synonyms
homolog
start1394172
stop1406432
direction+
length12261
essential
protein detected in LByes
Genomic Context

Functional category containing this gene/protein

Category
Subcategory1
Subcategory2
Subcategory3

Phenotypes of a mutant

plant-bacteria interaction

biocontrol of plant pathogens

Expression and Regulation

Operons
Transcripts
Primary TSS
Secondary TSS
Internal TSS1394421
Antisense TSS1394336

Sigma factors

Protein regulator

Additional regulation

RNA regulation_mode

This gene is a member of the following regulons

The protein


Catalyzed reaction/ biological activity
E.C. number
Protein family
Domains
Effectors of protein activity
Structure
Malonylation
"K2198,2251"
Acetylation
"K67,81,539,706,978,1209,1218,1505,1604,1874,1960,
Localization

Biological materials


Mutant
LacZ fusion
GFP fusion
FLAG-tag construct
Antibody
Additional information

References


Fan B, Li Y, Li L, P X,Bu C,Wu X, Borriss R.

Malonylome analysis of rhizobacterium Bacillus amyloliquefaciens FZB42 reveals involvement of lysine malonylation in polyketide synthesis and plant-bacteria interactions

J Proteomics. 2017 Feb 10;154:1-12. doi: 10.1016/j.jprot.2016.11.022;PMID:27939684

Liu L, Wang G, Song L, Lv B, Liang W

Acetylome analysis reveals the involvement of lysine acetylation in biosynthesis of antibiotics in Bacillus amyloliquefaciens.

Sci Rep. 2016 Jan 29;6:20108. doi: 10.1038/srep20108;PMID:26822828

Schneider K, Chen XH, Vater J, Franke P, Nicholso

Macrolactin is the polyketide biosynthesis product of the pks2 cluster of Bacillus amyloliquefaciens FZB42.

J Nat Prod. 2007 Sep;70(9):1417-23. Epub 2007 Sep 11.;PMID:17827323