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pdhC

pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase, subunit E2
genepdhC
locusRBAM_014440
feature typeCDS
productABS73807.1 pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase
synonyms
homologBSU14600
start1447788
stop1449116
direction+
length1329
essentialno
protein detected in LByes
Genomic Context

Functional category containing this gene/protein

CategoryMetabolism
Subcategory1Carbon metabolism
Subcategory2Carbon core metabolism
Subcategory3TCA cycle

Phenotypes of a mutant

plant-bacteria interaction

"transcription stimulated by root exudate, translation repressed by root exudate"

Expression and Regulation

Operons
pdhA-pdhB-pdhC-pdhD
Transcripts
Primary TSS
Secondary TSS
Internal TSS1447968
Antisense TSS

Sigma factors

SigA

Protein regulator

Additional regulation

"stringent response, negative regulation"

RNA regulation_mode

This gene is a member of the following regulons

SigA Regulon
The protein


Catalyzed reaction/ biological activity
E.C. number
2.3.1.12
Protein family
https://enzyme.expas
Domains
Effectors of protein activity
Refer to BSU14600
Structure
Refer to BSU14600
Malonylation
"K96,118,122,257,283,391"
Acetylation
"K55,226,254,257,266,322"
Localization

Biological materials


Mutant
LacZ fusion
GFP fusion
FLAG-tag construct
Antibody
Additional information
no ortholog in B. subtilis 168

References


Fan B, Li Y, Li L, P X,Bu C,Wu X, Borriss R.

Malonylome analysis of rhizobacterium Bacillus amyloliquefaciens FZB42 reveals involvement of lysine malonylation in polyketide synthesis and plant-bacteria interactions

J Proteomics. 2017 Feb 10;154:1-12. doi: 10.1016/j.jprot.2016.11.022;PMID:27939684

Liu L, Wang G, Song L, Lv B, Liang W

Acetylome analysis reveals the involvement of lysine acetylation in biosynthesis of antibiotics in Bacillus amyloliquefaciens.

Sci Rep. 2016 Jan 29;6:20108. doi: 10.1038/srep20108;PMID:26822828

Kierul K, Voigt B, Albrecht D, Chen XH, Carvalhai

Influence of root exudates on the extracellular proteome of the plant growth-promoting bacterium Bacillus amyloliquefaciens FZB42.

Microbiology. 2015 Jan;161(Pt 1):131-47. doi: 10.1099/mic.0.083576-0. Epub 2014 Oct 29;PMID:25355936

Fan B, Carvalhais, LC, Becker, A, Fedoseyenko D,

Transcriptomic profiling of Bacillus amyloliquefaciens FZB42 in response to maize root exudates

BMC Microbiol. 2012 Jun 21;12:116. doi: 10.1186/1471-2180-12-116.;PMID:22720735